The Prediabetes website is an educational resource developed by diabetes clinicians and academics.

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Testing & Management Guidelines

Consider higher risk groups

Older age, First Nations/Pasifika/East Asian ethnic background, family history of diabetes, history of gestational diabetes mellitus, polycystic ovary syndrome, overweight/obesity, greater waist circumference, unhealthy diet, sedentary behaviour, poor sleep, smoking, metabolic syndrome, and medications that can induce hyperglycaemia.

AUSDRISK

Use of the Australian Type 2 Diabetes Risk Assessment Tool (AUSDRISK) can estimate progression to type 2 diabetes over 5 years, and is a formal screening tool.

Diagnose

In Australia, prediabetes is defined by one or more of:

How is Prediabetes Detected?

There are three main blood tests used to diagnose prediabetes (and diabetes): glycated haemoglobin, a two hour 75g oral glucose tolerance test, or fasting blood glucose level.

fBGL

Fasting blood glucose level (fBGL) involves taking blood glucose level after your patient has not had anything to eat or drink for at least eight hours. This shows how well the body is able to modulate blood sugar in a fasted state.

75g OGTT

Two hour oral 75 g glucose tolerance test (75 g OGTT) is now rarely used in Australia for diagnosis of hyperglycaemia, except in pregnant women. You can explain that involves taking 75 grams of glucose as a sugary drink. Blood glucose levels are measured at baseline and two hours to determine how well the body’s insulin has processed the sugar.

HbA1c

Glycated haemoglobin, more commonly known as HbA1c, provides the longest term measure of blood sugar levels. You can explain to patients that it measures the amount of sugar bound to your red blood cells - cells that live for around three months. By testing HbA1c, you can diagnose prediabetes and diabetes, but also work out how well sugars have been under control over the past three months.

When Should I Re-Test?

For patients with normoglycaemia:

General population >40 years:
Use the AUSDRISK every 3 years or opportunistically to reassess risk.

Aboriginal and Torres Strait Islander people >18 years:
Test fBGL or HbA1c annually to screen, with OGTT for equivocal results.

High risk population >18 years (higher risk groups as above, or AUSDRISK ≥12):
Test fBGL or HbA1c annually to screen, with OGTT for equivocal results.

For patients with prediabetes:

Recheck fBGL or HbA1c annually; use OGTT in individuals with IGT.

For patients with diabetes:

Every three to twelve months, depending on the degree of hyperglycaemia and test used. Refer to specialist as required.

Don't forget the heart!

Prediabetes confers an independently increased risk of cardiovascular events such as heart attack and stroke. Many of the risk factors for diabetes are also risk factors for cardiovascular disease.

When screening with the AUSDRISK, consider also applying the Australian Heart Association CVD Risk Calculator.

Quiz: What Have You Learned About Prediabetes?

*Flip each card to reveal the correct answer.

What proportion of Australians are estimated to be living with prediabetes?

One in two
One in six
One in ten
One in one hundred

Answer

One in six

Which of the following is not associated with increased risk of prediabetes?

White bread
Raspberries
Potatoes
Ice cream

Answer

Raspberries

Which of the following is NOT diagnostic of prediabetes by Australian standards?

Fasting blood glucose of 6.1-6.9 mmol/L
2-hour blood glucose after 75 g glucose of 7.8-11.1 mmol/L
Random blood glucose of 6.1-6.9 mmol/L
HbA1c of 6.0-6.4%

Answer

Random blood glucose of 6.1-6.9 mmol/L